Molecular Weight of Hyaluronic Acid

Not All Hyaluronic Acid Serums Are the Same: Why Molecular Weight Matters

Melvory Hyaluronic Acide Serum

By now you may have heard us talk endlessly about the wonders of Hyaluronic Acid (HA). If not, you can read all about it here in this blog post, the first of our educational series on HA.


Hyaluronic Acid is the hydration hero commonly found in a multitude of products, from moisturisers to serums. It’s so widely used simply because it works!


What most people don’t realise however, is that not all Hyaluronic Acids are created equal.


As we continue our educational series on Hyaluronic Acid, we’re going to explore a concept called Molecular Weight 


We think it’s important that consumers have a basic understanding of what they’re putting on their skin and the Science behind their skincare products.


This empowers them to make informed choices about their purchases. 

So, what is Molecular Weight?

In skincare science, Molecular Weight refers to the size of the Hyaluronic Acid molecules. Some are large and others are tiny.


This matters because the size of the molecule determines how deep into your skin the Hyaluronic Acid molecules can reach.


Think of it this way …


Large molecules act as a comforting blanket, hydrating and protecting the surface.


Small molecules can reach deeper, delivering hydration below the surface, where processes relating to long-term skin health occur. 

Hyaluronic Acid Molecules Exist in Four Primary Sizes

Very High Molecular Weight (Sodium Hyaluronate Crosspolymer)
Very High Molecular Weight molecules form a protective, moisture-locking layer on the skin’s surface. They prevent water loss, boost immediate hydration and leave the skin feeling smooth, soft, and cushioned, like a silky barrier that seals everything in.


High Molecular Weight (Sodium Hyaluronate)
High Molecular Weight molecules stay on the skin’s surface. They deliver instant hydration, helping your skin to look plump and dewy. They also help to calm and soothe any dryness or irritation.


Medium to Low Molecular Weight (Sodium Acetylated Hyaluronate)
Medium Molecular Weight molecules penetrate just beneath the surface. They assist with skin elasticity and texture, and also play a role in supporting collagen production over time.


Low Molecular Weight (Hydrolyzed Sodium Hyaluronate)
Low Molecular Weight molecules are able to reach the deeper layers of your skin. They offer long-lasting hydration from within. They can also help to strengthen the skin barrier and improve firmness over time.

A Multi-Weight Hyaluronic Acid Formula is Best

Different sized Hyaluronic Acid molecules play different roles in the way that they deliver hydration, therefore a multi-weight formula is best.


Using a serum that consists of Hyaluronic Acid molecules that come in a single molecular weight is like watering only the top of a plant.


It helps with hydration temporarily, but the roots remain dry.


A formula that consists of HA molecules that come in multiple weights provides skin hydration at every level: surface, middle, and deep layers.


This is the key to achieving hydrated, nourished and plump skin. 

Melvory’s Hyaluronic Acid Formula is powered by four molecular weights

Melvory’s brand new Hyaluronic Acid Serum is made up of HA molecules that come in four different molecular weights, working together to create a 3D moisture matrix.


Inspired by the way a flower petal holds onto water, Melvory's HydraPetal Technology mimics the same multi-layer structure.


The unique, Science-backed formulation offers your skin complete, multi-layered hydration from the inside out. Each molecule is meticulously chosen to deliver targeted hydration, barrier support, and long-lasting plumpness.


There is currently nothing like this on the market right now, and we can't wait for you to experience the difference.


Instant plumpness? Check.
Lasting moisture? Absolutely.
Barrier support + deep nourishment? All in one.

It's safe for pregnancy and breastfeeding, and fragrance-free.